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KMID : 1149220200280020157
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Korean Journal of Oriental Medical Prescription
2020 Volume.28 No. 2 p.157 ~ p.167
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A Comparative Clinical Study on the Effect of Hwangryunhaedok-tang in Gastritis Treatment
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Park Beom-Chan
Kim Hee-Yeon
Kim Kwang-Youn
Yang Ju-Hye
Kim Kyung-Ho
Do Hyun-Ju
Jee Seon-Young
Choi Jun-Yong
Kim Young-Woo
Park Kwang-Il
Kim Ki-Bong
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Abstract
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Objectives : The purpose of this clinical study was to investigate the efficacy and safety of Hwangryunhaedok-tang on the gastritis treatment.
Methods : A total of 20 subjects who visited Pusan National University Hospital from April 2nd, 2019 to September 2nd, 2019 were included. In this study, we evaluated the individual symptoms through questionnaires, laboratory test, BIA (Bioelectrical Impedance Analysis), and adverse reaction according to medication. Statistical analysis was performed with paired t-test and Wilcoxon Signed Rank test. Statistical significance was achieved if the probability was less than 5% (p < 0.05).
Results : After medications, the total score of individual symptoms, primary outcome, was significantly decreased. In particular, individual symptoms such as upper abdominal pain, bloating, heartburn and trim showed significant improvement. However, no statistically significant differences were found in nausea/vomiting and anorexia. In additions, the laboratory test showed a statistically significant decrease in total cholesterol, but no statistically significant differences in results of BIA. In the safety evaluation, adverse reactions were not reported.
Conclusions : Considering this results, we have confirmed the possibility of Hwangryunhaedok-tang to the gastritis treatment.
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KEYWORD
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Hwangryunhaedok-tang, Gastritis, Clinical study
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